Publicatie 01-12-2024
Mission Statement: To advance the patient-centered, evidence-based practice of otolaryngology–head and neck surgery by publishing scientifically rigorous and innovative research, reviews, and commentary. Our journal serves as a vital resource for clinicians, researchers, educators, and trainees by providing high-quality, peer-reviewed content focused on improving the understanding and treatment of ear, nose, and throat conditions. We are dedicated to fostering dialogue and action on critical issues in otolaryngology, including the education and training of health care professionals, quality improvement, and the ethics and economics of equitable health care delivery.
Pubmed PDF WebHAJ Kim,MJ De Biasio,V Forte,RW Gilbert,JC Irish,DP Goldstein,JR de Almeida,MM Hanasono,P Yu,DB Chepeha,T Looi,CMKL Yao
Publicatie 01-12-2024
This combined in silico and in vitro study evaluates an optimal geometry of mandibular osteotomy that minimizes undesirable loading of the reconstruction plate.
Pubmed PDF WebMC Martinez,A Finegersh,FM Baik,FC Holsinger,HM Starmer,LA Orloff,JB Sunwoo,D Sirjani,V Divi,MM Chen
Publicatie 01-12-2024
This cohort study compares the prevalence of depression between adult patients with head and neck cancer and those with other cancers in the US.
Pubmed PDF WebR Shah,SG Wilkins,CW Safranek,HP Shah,C Brophy,S Mehra
Publicatie 01-12-2024
This cohort study aims to refine the understanding of human papillomavirus−positive oropharyngeal squamous cell carcinoma recurrence and inform optimal imaging surveillance strategies.
Pubmed PDF WebRM Ferrandino,J Barlow,B Gold,D Kraft,SA Roof,MS Teng,MN Khan,MH Berger,KJ Misiukiewicz,KK Sindhu,RL Bakst,MR Posner,WH Westra,EM Genden,RL Chai
Publicatie 01-12-2024
This diagnostic study assesses the performance metrics of tumor tissue–modified human papillomavirus (HPV) DNA testing for diagnosing oropharyngeal squamous cell carcinoma in patients with a lateral neck mass.
Pubmed PDF WebV Prasad,AS Parihar
Publicatie 01-12-2024
Physiological 2-deoxy-2-18Ffluoro-D-glucose (FDG) uptake in the oropharynx (OP) is commonly seen on positron emission tomography (PET), but it is the asymmetrical uptake that increases the diagnostic uncertainties often warranting further clarification. The literature on the incidence of oropharyngeal carcinoma in patients with incidental detection of asymmetrical FDG uptake is limited. In their retrospective cohort study, Armstrong et al evaluated the incidence of OP cancer (OPC) in patients showing asymmetrical FDG uptake in the OP. Patients with history or suspicion of malignancy in the OP were excluded. Based on clinically reported asymmetric FDG uptake in the OP in patients without an antecedent history or suspicion of an OP malignancy, they included 327 patients with a mean follow-up duration of 52.1 months. The PET/computed tomography (CT) imaging included in the data analyses spanned over 18 years. Almost every fifth patient was diagnosed with asymmetrical OP uptake on PET, yet only 5.5% of patients ultimately were diagnosed with OPC. The most frequent diagnosis was squamous cell carcinoma (n = 9) followed by lymphoma (n = 8) and sarcoma (n = 1).
Pubmed PDF WebMF Armstrong,BJ Burkett,TJ O'Byrne,HC Gottlich,LX Yin,KK Tasche,DL Price,EJ Moore,DM Routman,M Gamez,SC Lester,MA Neben-Wittich,DJ Ma,KA Price,VJ Lowe,KM Van Abel
Publicatie 01-12-2024
This cohort study evaluates the incidence of oropharynx cancer in patients with incidental asymmetric oropharynx positron emission tomography uptake.
Pubmed PDF WebSF Politano,E Georgiadi,A Bonifer,RG Muller,D Ludlow
Publicatie 01-12-2024
This cohort study evaluates whether in-office biopsies significantly improve time to biopsy and time to treatment compared with operating room biopsies.
Pubmed PDF WebJ Califano,P Sen,C Liu
Publicatie 01-12-2024
In the middle of the last century, smoking was touted as innocuous or even beneficial for health, with evidence of the association of tobacco carcinogens with cancer suppressed by a powerful tobacco industry. Subsequent decades of painstaking and definitive research and untold lives lost to tobacco-related disease were required to establish smoking as the leading cause of preventable death in the US, including and up to present day 2024. The study by Gallagher et al in JAMA Otolaryngology-Head & Neck Surgery shows an association between cannabis and head and neck cancer and raises the questions: are we repeating the same mistakes of the past we made with smoking, only now with marijuana and cannabis? Are we watching cannabis use rapidly expand with the support of a powerful industry, the public, and our legislators, only to discover years later, after the genie has escaped the bottle, that cannabis is carcinogenic? Understanding the differences and similarities between the biology of tobacco and cannabis will guide future research that will let us know if, in the words attributed to Yogi Berra, this is “déjà vu all over again.”
Pubmed PDF WebTJ Gallagher,RS Chung,ME Lin,I Kim,NC Kokot
Publicatie 01-12-2024
This cohort study examines the clinical association between cannabis use and head and neck cancer.
Pubmed PDF WebE Baran,M Lee,S Aviv,J Weiss,C Pettengell,I Karam,A Bayley,I Poon,KKW Chan,A Parmar,M Smoragiewicz,H Klieb,T Truong,P Maralani,DJ Enepekides,KM Higgins,A Eskander
Publicatie 01-12-2024
This diagnostic study investigates the accuracy of an artificial intelligence algorithm for staging oropharyngeal squamous cell cancer using data extracted from health records.
Pubmed PDF WebAS Ho,L Davies,MW Yeh
Publicatie 01-12-2024
In this issue of JAMA Otolaryngology–Head & Neck Surgery, Levyn et al report on conversion surgery for patients with low-risk papillary thyroid cancer (PTC) undergoing active surveillance (AS). Also known as delayed or rescue surgery, conversion surgery is an established part of the AS framework, one that to date has been perhaps underacknowledged. Most patients who undergo AS remain under observation, but a minority of people will require or desire intervention. Much debate has been made about the theoretical risks of delaying intervention: will there be upstaging, growth that unnecessarily jeopardizes important structures, and poorer outcomes? This study quells some of these concerns.
Pubmed PDF WebH Levyn,DW Scholfield,A Eagan,LA Boe,AR Shaha,RJ Wong,JP Shah,I Ganly,LGT Morris,RM Tuttle
Publicatie 01-12-2024
This cohort study examines the surgical, pathologic, and oncologic outcomes of patients with low-risk papillary thyroid carcinoma who underwent conversion surgery after a period of active surveillance.
Pubmed PDF Web